Approach to a Pregnant Woman with Anti D + Anti C Reactivity Pattern: A Diagnostic Conundrum
Published: September 1, 2017 | DOI: https://doi.org/10.7860/JCDR/2017/27902.10550
Preeti Rai, Geetika Sharma, Deeksha Singh, Jyoti Garg
1. Associate Professor, Department of Pathology, Lady Hardinge Medical College, New Delhi, India.
2. Assistant Professor, Department of Pathology, Lady Hardinge Medical College, New Delhi, India.
3. Senior Resident, Department of Pathology, Lady Hardinge Medical College, New Delhi, India.
5. Senior Resident, Department of Pathology, Lady Hardinge Medical college, New Delhi, India.
Correspondence
Dr. Deeksha Singh,
C1/04, Mangal Apartments, Vasundhara Enclave-110096, Delhi, India.
E-mail: deepshikha.singh293@gmail.com
The Rhesus G antigen is present on all RBCs that are C+ and also on most D+ RBCs. Due to this co-distribution of G with either C or D antigen, it mimics a reactivity pattern of anti C + anti D on Indirect Antiglobulin Test (IAT), though the role of Anti G in causing Hemolytic Disease of Newborn (HDN) is controversial. The differentiation of anti D, anti C, and anti G is essential particularly in pregnant females. We hereby report a rare case of anti G with anti D and anti C in a pregnant woman with emphasis on approach to identify anti D+C+G and its implications.
[
FULL TEXT ] | [ PDF]